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1

The changing face of immune tolerance induction in haemophilia A with the advent of emicizumab

Carcao, Manuel, Escuriola‐Ettingshausen, Carmen, Santagostino, Elena, Oldenburg, Johannes, Liesner, Ri, Nolan, Beatrice, Bátorová, Angelika, Haya, Saturnino, Young, Guy

Journal:

Year:

2019

Language:

english

File:

PDF, 544 KB

english, 2019

2

A clean analytical method for the spectrophotometric determination of formetanate incorporating an on-line microwave assisted hydrolysis step

M.J. Escuriola, A. Morales-Rubio, M. de la Guardia

Journal:

Analytica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 181 KB

english, 1999

3

When should prophylactic treatment in patients with haemophilia A and B start?— The German experience

C. A. Lee, C. M. Kessler, D. Varon, U. Martinowitz, M. Heim, W. KREUZ, C. ESCURIOLA-ETTINGSHAUSEN, M. FUNK, H. SCHMIDT, B. KORNHUBER

Journal:

Year:

1998

File:

PDF, 618 KB

1998

4

Modified magnetic resonance imaging score compared with orthopaedic and radiological scores for the evaluation of haemophilic arthropathy

M. B. FUNK, H. SCHMIDT, S. BECKER, C. ESCURIOLA, D. KLARMANN, T. KLINGEBIEL, W. KREUZ

Journal:

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

5

Prevention of joint damage in hemophilic children with early prophylaxis

W. Kreuz, C. Escuriola Ettingshausen, M. Funk, S. Pons, H. Schmidt, B. Kornhuber

Journal:

Year:

1999

Language:

german

File:

PDF, 91 KB

german, 1999

6

Radiological and orthopedic score in pediatric hemophilic patients with early and late prophylaxis

M. Funk, H. Schmidt, C. Escuriola-Ettingshausen, S. Pons, T. Dzinaj, C. Weimer, B. Kornhuber, W. Kreuz

Journal:

Annals of Hematology

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998

7

Recombinant vs. plasma-derived products, especially those with intact VWF, regarding inhibitor development

C. ESCURIOLA ETTINGSHAUSEN, W. KREUZ

Journal:

Year:

2006

Language:

english

File:

PDF, 500 KB

english, 2006

8

Inhibitor treatment in haemophilias A and B: summary statement for the 2006 international consensus conference

E. BERNTORP, A. SHAPIRO, J. ASTERMARK, V. S. BLANCHETTE, P. W. COLLINS, D. DIMICHELE, C. ESCURIOLA, C. R. M. HAY, W. K. HOOTS, C. A. LEISSINGER, C. NEGRIER, J. OLDENBURG, K. PEERLINCK, M. T. REDING, C

Journal:

Year:

2006

Language:

english

File:

PDF, 467 KB

english, 2006

9

The application of bypassing-agent prophylaxis in haemophilia A patients with inhibitors: a meeting report

L. A. VALENTINO, M. CARCAO, P. MATHEW, C. A. LEISSINGER, E. BERNTORP, V. BLANCHETTE, C. ESCURIOLA-ETTINGSHAUSEN, B. EWENSTEIN, N. EWING, A. GRINGERI, W. K. HOOTS, C. NEGRIER

Journal:

Year:

2009

Language:

english

File:

PDF, 63 KB

english, 2009

10

Early long-term FEIBA prophylaxis in haemophilia A patients with inhibitor after failing immune tolerance induction: A prospective clinical case series

C. ESCURIOLA ETTINGSHAUSEN, W. KREUZ

Journal:

Year:

2010

Language:

english

File:

PDF, 154 KB

english, 2010

11

Immune tolerance induction with a factor VIII concentrate containing von Willebrand factor (Haemoctin SDH®) in 14 patients with severe haemophilia A

C. BIDLINGMAIER, K. KURNIK, C. ESCURIOLA-ETTINGSHAUSEN, R. JAGER, R. KLAMROTH, C. MALE, A. MAROSI, L. NEMES, A. VON STACKELBERG, W. KREUZ

Journal:

Year:

2011

Language:

english

File:

PDF, 68 KB

english, 2011

12

Inhibitor Development in Patients with Hemophilia A after Continuous Infusion of FVIII Concentrates

CH von AUER, J. OLDENBURG, M. von DEPKA, C. ESCURIOLA-ETTINGHAUSEN, K. KURNIK, H. LENK, I. SCHARRER

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 6.23 MB

english, 2005

13

Management of bleeding disorders in children

E. BERNTORP, S. HALIMEH, A. GRINGERI, M. MATHIAS, C. ESCURIOLA, R. PÉREZ

Journal:

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

14

Epidemiology of Inhibitors in Haemophilia A

W. Kreuz, C. Escuriola-Ettingshausen, I. Martinez-Saguer, T. Güngör, B. Kornhuber

Journal:

Year:

1996

Language:

english

File:

PDF, 600 KB

english, 1996

15

Humoral immune responsiveness to a defined epitope on factor VIII before and after B cell ablation with rituximab

Christoph Kessel, Christoph Königs, Richard Linde, Carmen Escuriola-Ettinghausen, Hildegard Stoll, Thomas Klingebiel, Ursula Dietrich, Wolfhart Kreuz

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 733 KB

english, 2008

16

Protein-C concentrate for meningococcal purpura fulminans

Wolfhart Kreuz, Alex Veldman, Carmen Escuriola-Ettingshausen, Wilfried Schneider, Thomas Beeg

Journal:

Year:

1998

Language:

english

File:

PDF, 289 KB

english, 1998

17

The immune tolerance induction (ITI) dose debate: does the International ITI Study provide a clearer picture?

Ettingshausen, C. Escuriola, Kreuz, W.

Journal:

Year:

2013

Language:

english

File:

PDF, 132 KB

english, 2013

18

Portal vein thrombosis in a patient with severe haemophilia A and F V G1691A mutation during continuous infusion of F VIII after intramural jejunal bleeding – Successful thrombolysis under heparin therapy

C. Escuriola Ettingshausen, I. Martinez Saguer, W. Kreuz

Journal:

European Journal of Pediatrics

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

19

Platelet-dependent coagulation assays for factor VIII efficacy measurement after substitution therapy in patients with haemophilia A

Bassus, S., Wegert, W., Krause, M., Escuriola-Ettinghausen, C., Siegemund, A., Petros, S., Scholz, T., Scharrer, I., Kreuz, W., Engelmann, L., Kirchmaier, C. M.

Journal:

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

20

Factor VIII Products and Inhibitor Development in Severe Hemophilia A

Gouw, Samantha C., van der Bom, Johanna G., Ljung, Rolf, Escuriola, Carmen, Cid, Ana R., Claeyssens-Donadel, Ségolène, van Geet, Christel, Kenet, Gili, Mäkipernaa, Anne, Molinari, Angelo Claudio, Munt

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 551 KB

english, 2013

21

Influence of factor 5 rs6025 and factor 2 rs1799963 mutation on inhibitor development in patients with hemophilia A - an Israeli-German multicenter database study

Kenet, Gili, Bidlingmaier, Christoph, Bogdanova, Nadja, Ettingshausen, Carmen Escuriola, Goldenberg, Neil, Gutsche, Sven, Halimeh, Susan, Holzhauer, Susanne, Kurnik, Karin, Limperger, Verena, Junker,

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 335 KB

english, 2014

22

Development of an inhibitor-specific questionnaire for the assessment of health-related quality of life in haemophilia patients with inhibitors (INHIB-QoL)

Von Mackensen, S., Riva, S., Khair, K., Yee, T.T., Rocino, A., Escuriola, C., Oldenburg, J., Gringeri, A.

Journal:

Value in Health

Year:

2013

Language:

english

File:

PDF, 74 KB

english, 2013

23

Inhibitors in patients with haemophilia A

Kreuz, Wolfhart, Ettingshausen, Carmen Escuriola

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 290 KB

english, 2014

24

Miscibility of Poly(butyl acrylate)−Poly(butyl methacrylate) Sequential Interpenetrating Polymer Networks

Meseguer Dueñas, J. M., Escuriola, D. Torres, Gallego Ferrer, G., Monleón Pradas, M., Gómez Ribelles, J. L., Pissis, P., Kyritsis, A.

Journal:

Year:

2001

Language:

english

File:

PDF, 166 KB

english, 2001

25

A review of immune tolerance induction with Haemate ® P in haemophilia A

Escuriola Ettingshausen, C., Kreuz, W.

Journal:

Year:

2014

Language:

english

File:

PDF, 136 KB

english, 2014

26

Spotlight on the human factor: building a foundation for the future of haemophilia A management

Kessler, C., Oldenburg, J., Ettingshausen, C. Escuriola, Tiede, A., Khair, K., Négrier, C., Klamroth, R.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

27

Prophylaxis with FEIBA in paediatric patients with haemophilia A and inhibitors

Ewing, N., Escuriola-Ettingshausen, C., Kreuz, W.

Journal:

Year:

2015

Language:

english

File:

PDF, 192 KB

english, 2015

28

Inhibitor Development in Previously Untreated Patients with Hemophilia A: A Prospective Long-Term Follow-Up Comparing Plasma-Derived and Recombinant Products

Kreuz, Wolfhart, Ettingshausen, Carmen Escuriola, Zyschka, Alex, Oldenburg, Johannes, Saguer, Inmaculada Martinez, Ehrenforth, Silke, Klingebiel, Thomas

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

29

Factor VIII Inhibitors in Patients with Hemophilia A: Epidemiology of Inhibitor Development and Induction of Immune Tolerance for Factor VIII

Kreuz, Wolfhart, Becker, Sabine, Lenz, Elisabeth, Martinez-Saguer, Inmaculada, Escuriola-Ettingshausen, Carmen, Funk, Markus, Ehrenforth, Silke, Auerswald, Günther, Kornhuber, Bernhard

Journal:

Seminars in Thrombosis and Hemostasis

Year:

1995

Language:

english

File:

PDF, 1.09 MB

english, 1995

30

Long-term aspects of hemophilia B treatment

Ettingshausen, Carmen Escuriola, Kreuz, Wolfhart

Journal:

Blood Coagulation & Fibrinolysis

Year:

2004

Language:

english

File:

PDF, 68 KB

english, 2004

31

Role of von Willebrand factor in immune tolerance induction

Ettingshausen, Carmen Escuriola, Kreuz, Wolfhart

Journal:

Blood Coagulation & Fibrinolysis

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

32

Challenges of the management of severe hemophilia A with inhibitors

Mathieu, Sophie, Crampe, Carine, Dargaud, Yesim, Lavigne-Lissalde, Géraldine, Escuriola-Ettingshausen, Carmen, Tardy, Brigitte, Meley, Roland, Thouvenin, Sandrine, Stephan, Jean L., Berger, Claire

Journal:

Blood Coagulation & Fibrinolysis

Year:

2015

Language:

english

File:

PDF, 460 KB

english, 2015

33

Achievements, challenges and unmet needs for haemophilia patients with inhibitors

Dargaud, Y., Pavlova, A., Lacroix-Desmazes, S., Fischer, K., Soucie, M., Claeyssens, S., Scott, D.w., d'Oiron, R., Lavigne-Lissalde, G., Kenet, G., Escuriola Ettingshausen, C., Borel-Derlon, A., Lambe

Journal:

Year:

2016

Language:

english

File:

PDF, 635 KB

english, 2016

34

First prospective report on immune tolerance in poor risk haemophilia A inhibitor patients with a single factor VIII/von Willebrand factor concentrate in an observational immune tolerance induction study

Kreuz, W., Escuriola Ettingshausen, C., Vdovin, V., Zozulya, N., Plyushch, O., Svirin, P., Andreeva, T., Bubanská, E., Campos, M., Benedik-Dolničar, M., Jiménez-Yuste, V., Kitanovski, L., Klukowska, A

Journal:

Year:

2016

Language:

english

File:

PDF, 197 KB

english, 2016

35

Delayed diagnosis of hereditary angioedema

Martinez-Saguer, Inmaculada, Escuriola Ettingshausen, Carmen

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2016

Language:

english

File:

PDF, 126 KB

english, 2016

36

Type and intensity of FVIII exposure on inhibitor development in PUPs with haemophilia A

Marcucci, M., Mancuso, M. E., Santagostino, E., Kenet, G., Elalfy, M., Holzhauer, S., Bidlingmaier, C., Escuriola Ettingshausen, C., Iorio, A., Nowak-Göttl, U.

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 185 KB

english, 2015

37

Dielectric and dynamic mechanical studies on homogeneous PBA/PBMA interpenetrating polymer networks

Pissis, Polycarpos, Kyritsis, Apostolos, Meseguer Dueñas, José Maria, Monleón Pradas, Manuel, Torres Escuriola, Débora, Gallego Ferrer, Gloria, Gómez Ribelles, José Luis

Journal:

Macromolecular Symposia

Year:

2001

File:

PDF, 1.85 MB

2001

38

Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement

Iorio, A., Iserman, E., Blanchette, V., Dolan, G., Escuriola Ettingshausen, C., Hermans, C., Negrier, C., Oldenburg, J., Reininger, A., Rodriguez-Merchan, C., Spannagl, M., Valentino, L. A., Young, G.

Journal:

Year:

2017

Language:

english

File:

PDF, 132 KB

english, 2017

39

Age-Related Influence on the Clinical Course of Hereditary Angioedema Due to C1- Inhibitor Deficiency (HAE-C1-INH) – a Retrospective Study in 150 Adult Patients

Martinez-Saguer, Inmaculada, Escuriola-Ettingshausen, Carmen, Gutowski, Zeynep, Linde, Richard

Journal:

Journal of Allergy and Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 125 KB

english, 2017

40

Intensity of factor VIII treatment and the development of inhibitors in nonsevere hemophilia A patients: results of the INSIGHT case-control study

van Velzen, A. S., Eckhardt, C. L., Peters, M., Leebeek, F. W .G., Escuriola-Ettingshausen, C., Hermans, C., Keenan, R., Astermark, J., Male, C., Peerlinck, K., le Cessie, S., van der Bom, J.G., Fijnv

Journal:

Journal of Thrombosis and Haemostasis

Year:

2017

Language:

english

File:

PDF, 272 KB

english, 2017

41

Successful management of hereditary angioedema during pregnancy in a patient with heterozygous MTHFR mutation

Martinez Saguer, Inmaculada, Escuriola Ettingshausen, Carmen

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2017

Language:

english

File:

PDF, 191 KB

english, 2017

42

Risk Factors for the Progression from Low to High Titres in 260 Children with Severe Haemophilia A and Newly Developed Inhibitors

Mancuso, Maria Elisa, Fischer, Kathelijn, Santagostino, Elena, Oldenburg, Johannes, Platokouki, Helen, Königs, Cristoph, Escuriola-Ettingshausen, Carmen, Rivard, George, Cid, Ana, Carcao, Manuel, Ljun

Journal:

Thrombosis and Haemostasis

Year:

2017

Language:

english

File:

PDF, 213 KB

english, 2017

43

Immune tolerance induction: What have we learned over time?

Brackmann, H.-H., White, G.C., Berntorp, E., Andersen, T., Escuriola-Ettingshausen, C.

Journal:

Year:

2018

Language:

english

File:

PDF, 700 KB

english, 2018

44

The influence of individualized treatment on the quality of life (QoL) in 100 patients with Hereditary Angioedema (HAE C1-INH)

Saguer, Inmaculada Martinez, Ettingshausen, Carmen Escuriola, Gutowski, Zeynep, Linde, Richard

Journal:

Journal of Allergy and Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 126 KB

english, 2018

45

Prophylaxis re-visited: The potential impact of novel factor and non-factor therapies on prophylaxis

Carcao, M., Lambert, T., Leissinger, C., Escuriola-Ettingshausen, C., Santagostino, E., Aledort, L.

Journal:

Year:

2018

Language:

english

File:

PDF, 325 KB

english, 2018

46

Common themes and challenges in hemophilia care: a multinational perspective

Stoffman, J., Andersson, N. G., Branchford, B., Batt, K., D’Oiron, R., Escuriola Ettingshausen, C., Hart, D. P., Jiménez Yuste, V., Kavakli, K., Mancuso, M. E., Nogami, K., Ramírez, C., Wu, R.

Journal:

Hematology (Maney Publishing)

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

47

The importance of inhibitor eradication in clinically complicated hemophilia A patients

Oldenburg, Johannes, Young, Guy, Santagostino, Elena, Escuriola Ettingshausen, Carmen

Journal:

Expert Review of Hematology

Year:

2018

Language:

english

File:

PDF, 927 KB

english, 2018

48

Symptomatic Onset of Severe Hemophilia A in Childhood is Dependent on the Presence of Prothrombotic Risk Factors

Escuriola Ettingshausen, C., Halimeh, S., Kurnik, K., Schobess, R., Wermes, C., Junker, R., Kreuz, W., Pollmann, H., Nowak-Göttl, U.

Journal:

Thrombosis and Haemostasis

Year:

2001

Language:

english

File:

PDF, 39 KB

english, 2001

49

Inhibitors: A Need for Eradication?

Santagostino, Elena, Young, Guy, Escuriola Ettingshausen, Carmen, Jimenez-Yuste, Victor, Carcao, Manuel

Journal:

Acta Haematologica

Year:

2019

File:

PDF, 121 KB

2019

50

The burden of bleeds and other clinical determinants on caregivers of children with haemophilia (the BBC Study)

Khair, Kate, Klukowska, Anna, Myrin Westesson, Linda, Kavakli, Kaan, Escuriola, Carmen, Uitslager, Nanda, Santoro, Cristina, Holland, Mike, von Mackensen, Sylvia

Journal:

Year:

2019

Language:

english

File:

PDF, 859 KB

english, 2019